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What is Modafinil?

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Information on Modafinil

Modafinil is a type of oral drug used to improve wakefulness for patients who suffer from excessive sleepiness. This drug is very similar to Nuvigil (Armodafinil) and similar to amphetamines, Modafinil will promote wakefulness in the process of brain stimulation. The mechanism of modafinils exact action is unknown. It is believed that the drug works on increasing dopamine levels. It is available in many generic brands such as Modalert, Modafresh and Modvigil.

Dopamine is a type of chemical neurotransmitter and nerves use these transmitters to communicate with one another. Modafinil increases dopamine in areas of the brain by decreasing the re-uptake process of dopamine to the nerves. This drug received an approval from the FDA since December 1998. This is a prescription drug and to date there is no generic available. Modafinil is available in either tablets of either 100mg or 200mg and should be stored between temperatures of 15 up to 30C.

Modafinil is prescribed in patients to improve wakefulness in individuals who suffer from excessive sleepiness that is associated with obstructive sleep apnea or narcolepsy as well as shift work sleep disorder. The disorder known as narcolepsy is known as a type of chronic disease that affects the spinal cord and brain and is mainly characterized by an uncontrollable and recurrent desire and need to sleep.

The sleep disorder known as shift work sleep disorder is a type of condition where normal sleep rhythms of sleep are disturbed that has often resulted from individuals who work at night. The disorder sleep apnea is the type of condition where the individuals sleep is interrupted constantly during sleep due to shallow breathing or pauses in breathe from an obstruction in the individuals upper airway.


The general recommended dose for a patient is around 200mg once in a day. It is advisable not to exceed a dose of more than 400mg in a day. The drug is usually administered in the morning time when treating sleep apnea or narcolepsy and given an hour before work starts for individuals with shift work disorder. This drug should be taken without or with food and it is believed that the 400mg dose is not more effective compared to the 200mg.

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Drug Interactions

Modafinil can increase or decrease activities of the enzymes present in a liver that eliminate or metabolize other drugs. This can lead to a decrease in the levels of certain types of drugs that will decrease their effectiveness. Alternatively modafinil may increase the level of certain drugs that can cause toxicity. The modafinil treatment must be very carefully monitored when taken with other drugs.

The drugs that can have a decreased effectiveness when taken with the drug modafinil will include sandimmune (cyclosporine), theophyline as well as hormonal contraceptives like progestrin-only and progesterone and estrogen drugs like Ortho-Novum1/50 or Micronor. The effects caused from modafinil with hormonal contraceptives will occur when the hormones are taken in by implant, patch or mouth.

Drugs that have shown an increase in toxicity effects when taken with the drug modafinil will include rifampin, pnenobarbital, and carbamazephine. Other types of drugs like itraconazole and ketoconzole can reduce how effective modafinil will be. The drug known asmethylphenidate can delay the actions of the drug modafinil.

There have not been enough studies to assess the effects caused by Modafinil in women that are pregnant. Spontaneous abortion and intrauerine growth retardation however, has been reported. It is unknown if modafinil can be excreted into a nursing mothers breast milk. modafinil

Side Effects

The more common effects of modafinil include insomnia, anxiety, nervousness, nausea, upper respiratory tract infections and headaches. Modafinil can also cause types of seriously related skin disorders, abnormal heart rate, suicidal thoughts, psychosis, fainting,  high blood pressure and a number of organ hypersensitivity reactions. Always check with your doctor before you buy Modafinil online


Modafinil can reduce extreme sleepiness caused from sleep disorders like narcolepsy or obstructive sleep apnea. This medication can also be used by individuals who work schedules that can interfere with normal sleep patterns in order to stay awake when working. Modafinil will not substitute for lack of sleep and cannot be utilized to prevent sleep or treat tiredness in individuals who do not suffer from these disorders. This medication is not advised for and not recommended for use for children under the ages of 12. Modafinil should only be used under the advice of a health practitioner. Follow this link to buy Modafinil Online